Apparently a form of the passive participle of asah in the original sense of handling; rough (i.e. Sensibly felt); Esav, a son of Isaac, including his posterity -- Esau.
KJV: And after that came his brother out, and his hand took hold on Esau's heel; and his name was called Jacob: and Isaac was threescore years old when she bare them.
NASB: Afterward his brother came forth with his hand holding on to Esau's heel, so his name was called Jacob; and Isaac was sixty years old when she gave birth to them.